The Lord Jesus is speaking to the multitudes about the kingdom of heaven (Matthew 5-7), teaching them many truths, and he mentions dogs:
Matthew 7:6 Give not that which is holy unto the dogs, neither cast ye your pearls before swine, lest they trample them under their feet, and turn again and rend you.
The Lord Jesus dealing with a gentile woman from Canaan (Matthew 15:22) who came seeking healing for her daughter, rebuked her.
Matthew 15:26-27, Mark 7:27-28 But he answered and said, It is not meet to take the children’s bread, and to cast it to dogs. And she said, Truth, Lord: yet the dogs eat of the crumbs which fall from their masters’ table.
Read the whole account in Matthew 15:22-28, Mark 7:25-30. There are several lessons to be learned and among them is Matthew 15:24.
The Lord Jesus when teaching about what happens at the time of death, describes the sorry condition of Lazarus.
Luke 16:21 And desiring to be fed with the crumbs which fell from the rich man’s table: moreover the dogs came and licked his sores.
The apostles Paul and John describe false teachers:
Philippians 3:2 Beware of dogs, beware of evil workers, beware of the concision.
Revelation 22:15 For without are dogs, and sorcerers, and whoremongers, and murderers, and idolaters, and whosoever loveth and maketh a lie.
The apostle Peter quotes from a Proverb when he writes about those who knew about God but didn’t believe God.
2 Peter 2:22 But it is happened unto them according to the true proverb, The dog is turned to his own vomit again; and the sow that was washed to her wallowing in the mire.
Proverbs 26:11 As a dog returneth to his vomit, so a fool returneth to his folly.
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⇛ also see Dog (Old Testament), Dog (New Testament), Greyhound